Juan Carlos Montero
CANDIDATE
Juan Carlos Montero PhD. Biochemistry, 2004 is the author of 11 publications, one of which he is the principle author. All are international, and some have important highlights related to the theme of the project and are under the direction of Dr. Pandiella, who graduated with honours.
PROJECT
ErbB receptors and their ligands, and signalling Erk5 in translational cancer research.
The study involves the functional analysis proNeuregulia (proNRG) in breast cancer, by studying the functional properties of these proteins which are relevant for their biological and tumoural function. The studies involve a set inter-disciplinary approach to the problem, which include the majority of in vitro studies, and studies of gene signalling proNRG in samples of breast cancer patients and their possible correlation with clinical prognosis.
In addition, studying the other genes involved in the signalling path proNRG / Erb, including Erk5 kinase. Examination of the role of ERK5 in breast tumours and in animal samples which will be tested for the effects of constitutive activation of MEK5 in tumour genesis, and using patient samples.
CENTER
Cancer Research Center of Salamanca-IBMCC (CSIC)
GROUP
The team of Dr. Pandiella has a track record of significant scientific and academic international bibliographic seminal contributions in the field of ErbB signalling system. Undoubtedly, this guarantees the feasibility of the project and the scientific development.• D.P. Dr. Atanasio Pandiella
• D.C. Dr. Eugenio Santos